Antihistamines

Categories:

  • 1st Generation H1 receptor antagonists
    • May antagonize muscarinic receptors leading to anticholinergic effects
      • Decrease PNS = SNS effects
      • Urinary retention, retention due to impaired detrusor contraction
    • Azelastine (Astelin)
  • 2nd Generation H1 receptor antagonists
    • Fexofenadine (Allegra)
    • Loratadine (Claritin)
    • Desloratadine (Clarinex)
    • Cetirizine (Zyrtec)
      • SE: sedation, arrhythmias in overdose
  • H2 receptor antagonists
    • Cimetidine (Tagamet)
    • Famotidine (Pepcid)
    • Ranitidine (Zantac)

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